Police say two men opened fire after a brief argument in a parking lot along South Post Oak Road.
HOUSTON, TX — A 29-year-old man was shot and killed and his sister was wounded early Friday outside a nightclub in southwest Houston, police said. The gunfire erupted about 4:45 a.m. Nov. 28 in a parking lot at 11107 South Post Oak Road, where officers found both siblings with gunshot wounds.
Houston police identified the man as Mark Markquez. The woman, 30, was hospitalized and is expected to recover, according to investigators. Detectives said the pair had just left an establishment across the street when two men approached them in the lot. A brief exchange escalated into gunfire. The attack is under investigation by the Houston Police Department’s Homicide Division, which is reviewing surveillance video and gathering nearby witness accounts. As of Monday, Dec. 1, no arrests had been announced and investigators continued to search for the shooters and a vehicle seen leaving the area.
Officers were dispatched after 4:45 a.m. Friday to reports of shots fired near South Post Oak and South Willow. Responding units found the victims in the lot outside businesses just off the roadway. Paramedics took both to a hospital, where doctors pronounced the man dead. Investigators at the scene said the siblings had been walking back to their car from a nightlife venue when two men in dark clothing closed the distance and confronted them. Moments later, shots rang out. “Anyone with information in this case is urged to contact the HPD Homicide Division at 713-308-3600 or Crime Stoppers at 713-222-TIPS,” the department said.
Detectives said early evidence indicates the encounter began as a verbal dispute. Surveillance footage obtained by investigators shows two men firing at the siblings before fleeing. Police said the shooters were described as Black males wearing dark clothing. A light-colored sedan was seen leaving immediately after the gunfire, according to preliminary accounts reviewed by detectives. The woman was hit as the suspects ran off; she was stabilized at the hospital, authorities said. Markquez was shot in the upper body. The Harris County Institute of Forensic Sciences will determine the exact cause and manner of his death. Police have not announced a motive and said it remains unknown whether the shooters and victims knew each other.
The location sits along a busy corridor of South Post Oak Road that includes parking lots and late-night venues. Police have responded to several high-profile after-hours shootings in southwest Houston this year, including separate incidents near the corridor in November that drew large crowds and ended in gunfire. City leaders have said unregulated late-night gatherings can strain patrol resources and increase the risk of violence in surrounding neighborhoods. While each case is different, homicide detectives said they routinely look for shared patterns in location, timing and crowd size when assessing whether disputes that begin inside an establishment spill into nearby lots after closing.
Investigators said they will continue canvassing area businesses for video from late Thursday into early Friday, focusing on camera angles that capture both the sidewalk approach and the driveways leading to South Post Oak Road. Detectives are also seeking the sedan captured near the lot around the time of the shooting. No charges have been filed. If a suspect is identified, police said they will present the case to the Harris County District Attorney’s Office for review of potential murder and aggravated assault counts. The department said it will release additional details, including any composite descriptions or still images from surveillance, once they are confirmed.
By late morning Friday, crime scene tape ringed the lot as officers measured shell casing positions and photographed bullet strikes on pavement and nearby facades. Workers arriving to open nearby shops described pulling into the area and seeing patrol units lining South Post Oak. Some store employees said they recognized the siblings from previous late-night crowds but did not know their names. A police supervisor at the scene said the focus remained on securing the perimeter and preserving video from cameras mounted above storefronts and at the far edges of the property, where vehicles enter from the roadway.
As of Monday, police said the woman remained in stable condition and had provided an initial account to detectives. The investigation remains active. Detectives plan to release any confirmed vehicle details and additional suspect information as they verify evidence and interviews this week. A status update could come once lab processing begins on recovered casings and when additional surveillance footage is logged.
Author note: Last updated December 1, 2025.